Chimeric antigen receptor (CAR) redirected T cells are potent therapeutic options against hematological malignancies.The current dominant manufacturing approach for CAR T cells depends on retroviral transduction.With the advent of gene editing, insertion of a CD19-CAR into the T cell receptor (TCR) alpha constant (TRAC) locus using adeno-associated

Detecting the thickness of the top coal in a fully mechanized working face in advance can provide a basis for precise control of the top coal caving, which is beneficial to achieving a balance between the coal caving recovery rate and coal quality.By analyzing the principle of ground-penetrating radar detecting coal-rock interface and coal seam thi

The book under review is noteworthy because the analysis of the state personnel policy in the sphere of intellectual labor is carried out from the theoretical positions of reproduction of the socio-professional structure of society.The conclusions Ear Plugs based on theoretical postulates of the authors of the book are verified on the basis of rich

Different lubrication methods such as oil dip or injection lubrication are Lifestyle used in gearboxes to lubricate tribological contacts and to dissipate frictional heat.To improve resource and energy efficiency, novel needs-based lubrication methods like the drop-on-demand lubrication are being developed.It includes an ink-jet nozzle driven by a

Osteofibrous dysplasia occurs most frequently in the tibia and may result in deformity and pathological fracture.We Lifestyle report one such case in a 6-year-old girl who underwent minimally invasive plate osteosynthesis using a locking compression plate.The varus deformity of the tibia was manually corrected, and the plate was inserted without ex